Carbon nanotubes may have the same risk of asbestos
"Day by creating" an environment issue 7, 2008 Featured Articles published in the carbon nanotubes on human health effects reported. The first line in the product development need to reach people who need to pay attention to carbon: carbon nanotubes and asbestos is likely to have the same risk. Front-line staff, please be careful with caution to avoid inhaling.
The author is not to deny the new carbon nanotube materials. On the contrary, the author makes a high-strength materials, semiconductors, fuel cells have great quality and the possibility of very high expectations. Therefore, in addition to the advantages only hope that the reader, but also see the shortcomings of this material. Hope to establish safe storage and use of carbon nanotubes "risk management" approach to expand the scope of application of carbon nanotubes.
"Day by creating" story published in Japan, introduced the National Institute of Drug Safety Food Hygiene Research Centre biological toxicity test results the Department. See Journal of experimental conditions, in the experiment, when the mice come in contact with multi-layer carbon nanotubes, the higher the incidence of mesothelioma. The results suggest that carbon nanotubes may be as dangerous as asbestos.
However, for this experiment, for the following reasons: (1) subjects with the "p53 deficient mice *"; (2) is not input by the mouth, but the carbon nanotubes directly into the peritoneal; (3) a large number of inputs, so some experts said the results need to carefully look at. In fact, I first learned that the experimental results, we also hold the same concerns. However, I consulted the Minister of the Institute toxic Kanno pure, I feel that this experiment in "Toxicology" the fact is very reasonable. Kanno Minister explained below.
" (On (1) and (2)) past experience, out of recognition of a substance hazardous (dangerous, hazardous) for the purpose, and assumed that the material would cause mesothelioma cancer, intraperitoneal injection test with significant. carcinogenesis mechanism from view, p53 deficient mice are considered suitable for predicting mesothelioma cancer samples. " " (On (3)), we intend to launch a study on the toxicity of the maximum dose. If this dose failed to cause cancer, then the substance is completely 'safe'. Conversely, if the asbestos material with the same positive reaction to produce the same kind of tumor, then enough to doubt its 'harmful'. "
Indeed, Kaolv to the actual De work environment, work conducted in input, that were put into the mouth, then, can be further Tigao right Renti the impact of speculation O'clock in the Jing Du. But this experiment requires long time. By contrast, Kanno Minister and others pay more attention to the timeliness of warnings, choose to harm in the short term to confirm the experimental conditions. As expected, the results did not identify the "innocent." Conclusion is that "carbon nanotubes and asbestos-containing the same shape / size of the particles, there are significant risks. In labor management and product development need to pay attention to prevent inhalation."
I have previously introduced, asbestos induced mesothelioma for two main reasons. One of asbestos from the nose and mouth inhalation, will along the respiratory tract and bronchial deep into the lungs, to reach the air and blood oxygen, carbon dioxide in alveolar gas exchange. Of course, there is a variety of body defense mechanisms, enabling foreign body removed from the body together with the saliva, etc., but asbestos is invalid. This is because the asbestos is slender and small. Another reason is that the asbestos can not be dissolved, and has been retained in the body. In general, alveolar outside pH 7.4, weakly alkaline, and alveolar macrophages of the enzyme pH 4.8, was strongly acidic. In other words, the material can not withstand such strong acid chemical dissolution, it may persist in the body.
In summary, because of asbestos danger, "slender", "insoluble." And not in its chemical composition. Anti-speaking, as long as the asbestos is so "slim", "insoluble" materials, there is the same as the risk of asbestos. In the multi-layer carbon nanotubes, µm-sized fibrous or rod-like particle is the case.
Kanno Minister also ongoing experiments to answer questions raised by the author. Kanno Minister said that in the present experiment, the amount of carbon nanotubes put down to the previous experiments 1 / 10, 1 / 100, 1 / 1000. Although the results can not open, but in all the experiments, the mice appeared mesothelioma.
Via: Carbon nanotubes may have the same risk of asbestos
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